Biochemical Reagents, JP-2-196, Molecular glue handle, CAS 2913587-31-0, 98% by HPLC/NMR (Conforms), JP-2-196 is a unique molecular glue chemical handle that binds several RING E3 ligases including RNF126, RNF40, MID2, RNF219, RNF14, and LRSAM1. Has been shown to induce proteasomal degradation of a wide variety of proteins when linked to the appropriate ligand.